ALPHAZER
Acetyl L-carnitine 60 capsules

Acetyl-L-carnitine (also called ALCAR or L-acetylcarnitine) is a molecule derived from the acetylation of L-carnitine: both of these amino acids are present in large quantities in cells and tissues. Acetylcarnitine is a key element in the oxidation of fatty acids and their breakdown to produce energy. This process is particularly important because fatty acids are the main 'food' for the mitochondria, the energy centres of the cells that make up our complex human body. As the carrier molecule for fatty acids, acyl-CoA, cannot cross the cell membrane, a carnitine deficiency causes a reduction in the concentration of fatty acids in the mitochondria and, consequently, reduced energy production.

What is Acetyl-L-Carnitine?

Generally speaking, carnitine is a non-protein amino acid (i.e. it does not form proteins), and is the compound responsible for transporting long-chain fatty acids into the cellular energy-producing units: the mitochondria. It performs many other physiological functions, including ketoacid conversion of branched-chain amino acids (valine, leucine and isoleucine), which is extremely important during fasting and exercise.

This acetylated version of L-carnitine is more bioavailable than its 'simple' form, which also has an effect on mitochondrial energy, making it an even more effective transporter of fatty acids. In addition, ALCAR easily crosses the blood-brain barrier: its field of action extends to the nervous system, where it exerts a nootropic and neuroprotective action.

This molecule is proving to be a real 'nootropic', i.e. a substance capable of improving cognitive activities. As noted above, this form, which is able to cross the blood-brain barrier, has several important properties: it can increase acetylcholine levels in the synapse, improve memory (and cognitive processes in general) and have a stimulating and energising effect on the body and mind, both to alleviate the symptoms of fatigue in the elderly and to support muscle recovery in athletes. In long-duration physical activities, it has a positive effect on maximum heart rate and even reduces muscle pain, an effect that is particularly welcome in endurance athletes.

Acetylcarnitine also has interesting antioxidant activities, which make it an important neuroprotective agent for the brain.

Benefits of our supplement

Why choose Acetyl L-carnitine?

    Improves oxidation of fatty acids;
    Improves cognitive activities;
    Supports memory;
    Has an energising effect on body and mind;
    Alleviates symptoms of fatigue in the elderly;
    Supports muscle recovery in athletes;
    It is the most bioavailable form.

When and how to take it

Take 1 capsule a day with water. In order to reduce fatigue and improve energy levels during a training session, we recommend taking it about 30 minutes beforehand.

Net content: 82g

Warnings: do not exceed the recommended daily dose. Supplements are not intended as a substitute for a varied diet. A varied and balanced diet and a healthy lifestyle are important. Keep out of the reach of children under three years of age. Do not use in pregnancy and in children, or in any case for prolonged periods, without consulting a doctor. Keep in a cold and dry place. Avoid exposure to heat sources and sunlight.

 

Bibliography

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Fielding R, Riede L, Lugo JP, Bellamine A. l-Carnitine Supplementation in Recovery after Exercise. Nutrients. 2018 Mar 13;10(3):349. doi: 10.3390/nu10030349. Erratum in: Nutrients. 2018 Apr 26;10(5): PMID: 29534031; PMCID: PMC5872767.

 

Pekala J, Patkowska-Sokoła B, Bodkowski R, Jamroz D, Nowakowski P, Lochyński S, Librowski T. L-carnitine--metabolic functions and meaning in humans life. Curr Drug Metab. 2011 Sep;12(7):667-78. doi: 10.2174/138920011796504536. PMID: 21561431.

 

Gnoni A, Longo S, Gnoni GV, Giudetti AM. Carnitine in Human Muscle Bioenergetics: Can Carnitine Supplementation Improve Physical Exercise? Molecules. 2020 Jan 1;25(1):182. doi: 10.3390/molecules25010182. PMID: 31906370; PMCID: PMC6982879.

 

Longo N, Frigeni M, Pasquali M. Carnitine transport and fatty acid oxidation. Biochim Biophys Acta. 2016 Oct;1863(10):2422-35. doi: 10.1016/j.bbamcr.2016.01.023. Epub 2016 Jan 29. PMID: 26828774; PMCID: PMC4967041.