ALPHAZER
Beta Alanine Cambridge Assured™ 120 tablets

ALPHAZER® BETA ALANINE Cambridge Assured™

There β-Alanina is a non-protein amino acid precursor of carnosine, a dipeptide synthesized from β -Alanine and L-Histidine, which has been shown to buffer the pH of skeletal muscle helping to delay the onset of muscle acidosis induced by lactic acid.

Several studies suggest that the continued intake of β-alanine allows to increase the concentration of carnosine in skeletal muscle. Furthermore, a positive correlation between carnosine present in muscle and some parameters used to measure physical performance at high intensity seems to be proven.

Quality first of all
Alphazer® relies exclusively on certified and accredited raw materials.
For the BCAA line, we chose raw materials from Cambridge Commodities.
Raw materials certified grade A for the BRC Global Standard for Food Safety Issue 8 and produced in facilities registered by Informed-Sport.
Once the raw material arrives in Italy, it undergoes stringent quality tests.
Lots are sampled and tested and then the finished product is manufactured according to regulations and produced in Italian plants.
In addition to analyses on intolerances such as gluten and lactose.

In the panorama of dietary supplements in the world of sport, one of the most popular and interesting ones, whose efficacy has been investigated by research, is Beta-Alanine.

When you reach a certain intensity with physical activity, there is an increase in hydrogen ions (H+) which tend to accumulate in muscle cells, generating a decrease in cellular pH, favouring a very 'acidic' environment, which comes to compromise the effectiveness of muscle contraction which becomes less and less efficient, favouring the onset of muscle fatigue to the point of risking compromising performance, or worse, a competition.

Once the non-essential amino acid β-alanine has been introduced orally, it will be combined with L-histidine to synthesise a dipeptide that will be the real player in the 'buffer' effect on lactate, namely carnosine. In muscles, histidine levels are normally high and Beta Alanine levels low, which limits carnosine production. Supplementation with Beta Alanine has been shown to raise carnosine levels in muscles by 80%, and will act as a hydrogen ion neutralising agent, reducing the build-up of unpleasant lactic acid in muscles, significantly reducing muscle fatigue, as well as being an excellent antioxidant against free radicals. If Carnosine were taken directly orally, it would be significantly degraded with poor bioavailability, so it is advisable to use its 'precursor', Beta-alanine, for truly effective results. And as research has shown, and more and more athletes are saying: ..... works! This translates into increased strength performance in body-building workouts, and is very popular in sprinting sports such as cycling, athletics or crossfit, where it enables greater performance, greater resistance to fatigue and more endurance. Many users also report intense vasodilation, with the associated perception of increased muscle pumping when taken before training. This is due to the fact that canosine has an effect on stimulating nitric oxide synthesis. However, it has been observed that for Beta-Alanine supplementation to have "effective" concentrations, it takes a relatively short time (approximately 2 weeks), and the greatest effect of its supplementation can be appreciated by the athlete after a longer period (between 4 and 10 weeks).

*Abtaining excessive amounts of Beta Alanine can cause "paresthesia", a sensation typically described as "tingling of the skin", which occurs particularly on the face, neck and back of the hands within minutes of ingestion.

SCIENTIFIC REFERENCES

Saunders B et al. β-alanine supplementation to improve exercise capacity and performance: a systematic review and meta-analysis. Br J Sports Med. 2017 Apr;51(8):658-669.

Hobson RM et al. Effects of β-alanine supplementation on exercise performance: a meta-analysis. Amino Acids. 2012 Jul;43(1):25-37.

Dankel SJ et al. Do metabolites that are produced during resistance exercise enhance muscle hypertrophy? Eur J Appl Physiol. 2017 Nov;117(11):2125-2135.

Iraki J et al. Nutrition recommendations for bodybuilders in the off-season: A narrative review. Sports. 2019;7,154.

Hoffman J et al. Effect of creatine and beta-alanine supplementation on performance and endocrine responses in strength/power athletes. Int J Sport Nutr Exerc Metab. 2006 Aug;16(4):430-46.

Liu Q et al. Mechanisms of itch evoked by beta-alanine. J Neurosci. 2012;(32):14532-14537,

Artioli GG, Gualano B, Smith A, Stout J, Lancha AH Jr. Role of beta-alanine supplementation on muscle carnosine and exercise performance. Med Sci Sports Exerc. 2010 Jun;42(6):1162-73.

Saunders B, Sale C, Harris RC, Sunderland C. Effect of beta-alanine supplementation on repeated sprint performance during the Loughborough Intermittent Shuttle Test. Amino Acids. 2012 Jul;43(1):39-47.

Smith AE, et al. Effects of beta-alanine supplementation and high-intensity interval training on endurance performance and body composition in men; a double-blind trial. J Int Soc Sports Nutr. 2009 Feb 11;6:5