YAMAMOTO NUTRITION
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YAMAMOTO® NUTRITION
ArginineMICRO is a food supplement that provides 2000 mg of arginine per daily dose. ArginineMICRO is a food supplement that provides 2000 mg of arginine per daily dose. The active ingredients present in supplements play some important physiological roles in case of low intake with diet or increased need (for example with physical activity). In some cases, however, their activity may be limited due to low solubility, stability or bioavailability. The patented MCU-20® microencapsulation system optimizes solubility and absorption in order to obtain a more efficient release of active ingredients, increasing their ability to interact with the body. The active ingredients are encapsulated within a vesicle which can be 1 - 10 µm in size. A single dose can contain millions of microcapsules, each capable of releasing the active ingredients in the body. What is microencapsulation?
The microencapsulation already present in the world of food and pharmaceuticals, today has allowed an important turning point in limits that conditioned the bioavailability of many molecules in the world of food supplementation. The microencapsulation process from which MCU-20® is born is the result of an innovative technology that allows the maximization of the transport and the relative absorption of the nutritional elements that we want to arrive unharmed and at the best of their bioavailability to maximize their effect .Many raw materials commonly used in the world of supplements have limits of various kinds, starting from a possible degradation in the gastrointestinal tract due to "environmental" conditions or to the poor solubility of the material, which can form precipitates that cannot be completely absorbed ( in the face of a considerable waste and economic cost).
What does MCU-20® technology consist of? Thanks to the patented MCU-20® microencapsulation technique, the raw material is first dried quickly without affecting the physico-chemical properties of the element, and then it is fragmented into extremely small microgranules and then "trapped" in thin films of a microencapsulating agent, which will allow not only to protect and isolate the raw material, but also to be able to limit any unpleasant odors. Thanks to MCU-20® it has been allowed to amino acids, which are characterized by low solubility and stability in water, to enter a new era, whose luster of effectiveness is enhanced in being able to be made quickly and completely soluble, without the formation of precipitates, for a much higher absorption.
This technology has also been able to allow other raw materials typical of sports supplementation to be able to overcome the limits of oral absorption that they may present, from creatine, to l-carnitine or arginine. Thanks to the MCU-20® technology, these elements, defined as "poorly absorbed", can demonstrate their effectiveness by bypassing environmental chemical or enzymatic limits, providing a protective and transport carrier to the small microparticles. which will reach a unique bioavailability . Are you sure you are absorbing what you take?
Often active ingredients such as amino acids and derivatives are partially absorbed. Just think of Glutamine, which is absorbed for 60 - 80% by the intestine; the remainder is too little to meet the needs of our muscles. With MCU-20® microencapsulation technology, Glutamine passes the gastrointestinal tract unscathed to be absorbed 100%. The same is true for Arginine where about 40% of the dose introduced orally is lost and degraded by gastric juices. Or the case of Creatine where intestinal enterocytes are unable to absorb bulky micro-crystals of creatine. And taking creatine together with high glycemic index carbohydrates could be ideal for optimizing their absorption but counterproductive for those on a diet.the MCU-20® microencapsulation technology effectively guarantees 100% absorption of the active ingredients involved!
Don't mind the price, but mind the price / absorption ratio! With Yamamoto® MCU-20® products, what you buy is assimilated! 5 grams of standard Glutamine is assimilated at 20 - 40%. So 1 or at most 2 grams. With the MCU-20® technology on 5 grams taken, 5 are assimilated! MCU-20®: - Preserves the functional ingredients thermolabile or susceptible to oxidation during the transformation and / or conservation processes
- Preserves functional ingredients from adverse gastric conditions to allow them to arrive at the site of interest
- Guaranteed absorption of functional ingredients, even those elements defined as "poorly absorbed" such as amino acids, carnitine and creatine
- Mask unwanted flavors
- Prevents unwanted reactions between the ingredient of interest and the surrounding matrix
Quality first of all
Yamamoto® Nutrition relies exclusively on certified and accredited raw materials.
For the BCAA line, we chose raw materials from Cambridge Commodities. Raw materials certified grade A for the BRC Global Standard for Food Safety Issue 8 and produced in facilities registered by Informed-Sport. Once the raw material arrives in Italy, it undergoes stringent quality tests. The batches are sampled and tested and then the finished product is manufactured according to regulations and produced in Italian plants. In addition to analyses on intolerances such as gluten and lactose. Arginine is a "conditionally essential" amino acid widely found in protein foods and in nature. It is in fact nutritionally essential for newborns and in the early stages of life, as they are not yet able to synthesize it. Arginine is an amino acid that plays a fundamental role in the formation of nitric oxide (NO), in turn involved in the regulation of a series of physiological functions that include muscle tone, mitochondrial respiration, the uptake of glucose in the muscle. skeletal, and cellular calcium kinetics.
As adults, it is an amino acid that is no longer essential as it is easily integrated with the diet, but will continue to play its valuable roles such as eliminating toxins (see ammonia) and free radicals responsible for inflammation, in healing wounds. , for the immune system and aging. The importance of arginine, however, finds fame with the production of nitric oxide, a "key" molecule for the functioning of the cardiovascular system and at the brain level, arginine is involved in cellular communication through neurotransmitters.
In addition to the detoxifying action from ammonia, arginine intervenes in the biochemical processes of synthesis of Protein, sugars and for complex molecules such as hemoglobin, insulin, collagen, elastin and creatine. Although historically used also in the clinical setting, oral Arginine supplementation has many limits for its bioavailability, even if in the world of sports supplementation, in particular body building, it is still often included in "pre-workout" supplements for production of nitric oxide, with the aim of creating a greater flow of blood, the "pump", rich in oxygen and nutrients to be supplied to the muscles.
But why is it defined as an "outdated" supplement? It is now established that today there are better and more effective products for this functionality, as the integration of arginine is not very effective in practice, to favor a worthy rewarding pump of relief for the most demanding body builder. This is because the arginase enzyme compromises much of its bioavailability, creating a very high degree of degradation in by-products such as urea and ornithine. To get to the "useful" dosages to guarantee that "skin-tearing" pump you are looking for, it is necessary to take high dosages that could easily generate diarrhea.
But thanks to the new patented Yamamoto® Nutrition MCU-20® transport technology, the problem of absorption limits has been solved for many raw materials, and so for arginine. Thanks to this innovative system, we are able to increase the solubility and improve the absorption of the elements, and as in the case of arginine, it is possible to "protect" it and make it "unassailable" to ensure its transport to the absorption site, and then benefit its effects on nitric oxide stimulation.
SCIENTIFIC REFERENCES Böger RH. The pharmacodynamics of L-arginine. Altern Ther Health Med. 2014 May-Jun;20(3):48-54. PMID: 24755570. Palmer RM. The L-arginine: nitric oxide pathway. Curr Opin Nephrol Hypertens. 1993 Jan;2(1):122-8. doi: 10.1097/00041552-199301000-00018. PMID: 7522910. Wu G, Morris SM Jr. Arginine metabolism: nitric oxide and beyond. Biochem J. 1998 Nov 15;336 ( Pt 1)(Pt 1):1-17. doi: 10.1042/bj3360001. PMID: 9806879; PMCID: PMC1219836. Bansal V, Ochoa JB. Arginine availability, arginase, and the immune response. Curr Opin Clin Nutr Metab Care. 2003 Mar;6(2):223-8. doi: 10.1097/00075197-200303000-00012. PMID: 12589193. Martin S, Desai K. The effects of oral arginine on its metabolic pathways in Sprague-Dawley rats. Br J Nutr. 2020 Jan 28;123(2):135-148. doi: 10.1017/S0007114519002691. Epub 2019 Dec 18. PMID: 31647043. Dr. Gabriele Trapani DIRECTIONS: take 2 tablets a day with water.
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| Nutrition information |
Per daily dose (2 tablets) |
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L-arginine (Cambridge Assured™)
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2000 mg |
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Ingredients: L-arginine Cambridge Assured™ (contains glazing agent: hydroxypropylcellulose), bulking agents: cellulose, dicalcium phosphate; anti-caking agents: silicon dioxide, magnesium salt of fatty acids. |
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