YAMAMOTO NUTRITION
|
|||||||||||||||||||||||||||||
 YAMAMOTO® NUTRITION
Yamamoto® Nutrition Joint SUPPORT Joint SUPPORT is a food supplement of glucosamine, MSM, hyaluronic acid and plant extracts, suitable for adult sportsmen who practice intense physical activities. JOINT SUPPORT is indicated in those cases where it is necessary to support joint function (Curcuma, Boswellia) and to contrast localized states of tension (Boswellia). Healthy and efficient joints mean functionality, smooth movement and flexibility. The joints are essential elements for the movement of any athlete and need supportive protection due to the stress induced by intense physical activity with continuous and repeated stresses. Age also has a further impact on the joints, causing wear of the cartilage, which can lead to recurrent inflammation, arthritis, decreased mobility that will affect training and performance. Our performance depends on the ability of our body, our muscles, to move quickly and efficiently and joint health can make the difference to a satisfying workout, progression to results as well as between leaving a competition or ... win it. And the first factor for the athlete is being able to train, so taking care of the joints means maintaining flexibility, decreasing joint inflammation and stiffness, supporting connective tissue and bone matrix, promoting healthy synovial fluid with an ad hoc lubricated joint. .
We can provide help through specific supplements formulated with really effective elements that act on these fronts, such as Joint Support in its most recent version.Joint Support is a food supplement to support joint function based on: glucosamine, MSM, Turmeric and Boswellia both in high absorption versions for real effectiveness, and hyaluronic acid. Glucosamine is an amino sugar that occurs naturally in the connective tissues that surround and cushion the joint, including cartilage, tendons and ligaments, as well as the synovial fluid that lubricates the joints. Its main action concerns its activity of strengthening the joints and helping to preserve the structure and degree of elasticity of the cartilage.
Methylsulfonylmethane (MSM) is a stable, rich and natural source of organic sulfur that tends to decline considerably with aging. Methylsulfonylmethane is a highly assimilable micronutrient by our body, as a precious source of organic sulfur that we know to be found in various sulfuric components of our body, so much so that it ranks third among the most important minerals in the body. Organic sulfur is a "biologically active" compound that plays a decisive role in various components and mechanisms of the human body, is part of the composition of different amino acids, is a fundamental element in the constitution of joint cartilage and connective tissues such as the dermis of the skin. Speaking of inflammation, turmeric, as a popular food spice derived from the tradition of Ayurvedic medicine, is today not only considered a true "superfood. Curcumin among these is more associated with the anti-inflammatory action of joint tissues, promoting support and flexibility, in reducing articular destructive oxidative stress, in acting against COX-2, MMP and "AGE" (end products of advanced glycation). Curcumin promotes the synthesis of collagen and other structural joint Protein, simultaneously protecting from enzymes that alter or "wear out" the structure of the joints, improving joint stiffness and comfort, thereby relieving joint pain.
Unfortunately, turmeric as a spice has a poor bioavailability, so to optimize its benefits, it was included in the Curcugreen ™ BCM-95® version, which through a particular extraction process was taken and mixed the group of curcuminoids present in the root with the essential oils including (RI) -turmerone by optimizing their bioactive Energy and allowing a unique absorption and synergy of action that has shown an extraordinary bioavailability from 7 to 9 times higher than that of the most common turmeric extracts at 95% standardization . Curcugreen ™ BCM-95®, is one of the most studied and recognized versions of turmeric in the international literature and uses a dossier of over 50 clinical studies and 15-year quality-safety control monitoring. In favor of a powerful and effective anti-inflammatory action on the joints, Joint Support boasts in its formulation the presence of Boswellia, a botanical species of the incense family, widespread in Africa, in particular in the Arabian Peninsula and in India where its medical use was well recognized by the Ayurvedic tradition. Boswellia, thanks to the precious gummersins that are extracted, rich in boswellic acids, tetracyclic acids and polysaccharides, is finding a great diffusion also in the modern - western world in sports supplements. The mechanism of action concerns in this case the action on the 5-lipoxygenase enzyme as an active agent responsible for the production of substances that facilitate inflammatory processes, as well as being able to inhibit elastases, highly destructive enzymes, which attack and deteriorate the elastic part of the tissues in which an inflammatory process is underway. Joint Support to ensure maximum yield from this additional element, contains BosLiQ®, a patent in which the extract present is highly bioavailable, characterized by the presence of oleananic, ursanic and ursanic lipophilic pentacyclic triterpene acids and their esters and by the presence of high quantities of AKBA, of volatile compounds with bioactive properties (incensol, incensol acetate) which results in a powerful anti-inflammatory and contrasting response to painful processes, in favor of effective joint protection with an interesting scientific literature to support it. that attack and deteriorate the elastic part of the tissues in which an inflammatory process is in progress. Joint Support to ensure maximum yield from this additional element, contains BosLiQ®, a patent in which the extract present is very bioavailable, characterized by the presence of oleanananic, ursanic and ursanic lipophilic pentacyclic triterpene acids and their esters and by the presence of high quantities of AKBA, of volatile compounds with bioactive properties (incensol, incensol acetate) which results in a powerful anti-inflammatory and contrasting response to painful processes, in favor of effective joint protection with an interesting scientific literature to support it. that attack and deteriorate the elastic part of the tissues in which an inflammatory process is in progress. Joint Support to ensure maximum yield from this additional element, contains BosLiQ®, a patent in which the extract present is highly bioavailable, characterized by the presence of oleananic, ursanic and ursanic lipophilic pentacyclic triterpene acids and their esters and by the presence of high quantities of AKBA, of volatile compounds with bioactive properties (incensol, incensol acetate) which results in a powerful anti-inflammatory and contrasting response to painful processes, in favor of effective joint protection with an interesting scientific literature to support it.
And if we talk about preventive support or recovery for the joints, in the synergy of the elements that make up Joint Support, hyaluronic acid could not be missing, a glycosaminoglycan naturally present in the connective tissue of joints, in the skin and in high concentration in the synovial fluid, consisting of the aggregation of disaccharide units formed by residues of glucuronic acid and N-acetylglucosamine. During joint inflammation, it is good to know that the structure of hyaluronic acid is attacked by pro-inflammatory elements (called with "hyaluronidase activity"), thus losing its structural characteristics and its important lubricating function. The intake of hyaluronic acid of the correct (high in this case) molecular weight becomes important, as it is able to enclose water molecules and promote the restoration of the viscosity of the synovial fluid at the level of the joints, obtaining a better effect on mobility by acting as an effective lubricating agent. At the level of the cartilage, hyaluronic acid binds to proteoglycans, forming large aggregates, which support the stability of the cartilage itself.
SCIENTIFIC LITERATURE
Yoshimura, M., Sakamoto, K., Yamamoto, T., Ishida, K., Yamaguchi, H., & Nagaoka, I. (2009). Evaluation of the effect of glucosamine administration on biomarkers for cartilage and bone metabolism in soccer players. International journal of molecular medicine, 24(4), 487-494. Momomura, R., Naito, K., Igarashi, M., Watari, T., Terakado, A., Oike, S., … & Kaneko, K. (2013). Evaluation of the effect of glucosamine administration on biomarkers of cartilage and bone metabolism in bicycle racers. Molecular medicine reports, 7(3), 742-746. Ostojic, S. M., Arsic, M., Prodanovic, S., Vukovic, J., & Zlatanovic, M. (2007). Glucosamine administration in athletes: effects on recovery of acute knee injury. Research in Sports Medicine, 15(2), 113-124. Kim LS, Axelrod LJ, Howard P, Buratovich N, Waters RF. Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. Osteoarthritis Cartilage. 2006 Mar;14(3):286-94. doi: 10.1016/j.joca.2005.10.003. Epub 2005 Nov 23. PMID: 16309928. Butawan M, Benjamin RL, Bloomer RJ. Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement. Nutrients. 2017 Mar 16;9(3):290. doi: 10.3390/nu9030290. PMID: 28300758; PMCID: PMC5372953. Tennent DJ, Hylden CM, Kocher BK, Aden JK, Johnson AE. A randomized controlled trial evaluating methylsulfonylmethane versus placebo to prevent knee pain in military initial entry trainees. US Army Med Dep J. 2017 Oct-Dec;(3-17):21-25. PMID: 29214616. Withee ED, Tippens KM, Dehen R, Tibbitts D, Hanes D, Zwickey H. Effects of Methylsulfonylmethane (MSM) on exercise-induced oxidative stress, muscle damage, and pain following a half-marathon: a double-blind, randomized, placebo-controlled trial. J Int Soc Sports Nutr. 2017 Jul 21;14:24. doi: 10.1186/s12970-017-0181-z. PMID: 28736511; PMCID: PMC5521097. Debbi EM, Agar G, Fichman G, Ziv YB, Kardosh R, Halperin N, Elbaz A, Beer Y, Debi R. Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: a randomized controlled study. BMC Complement Altern Med. 2011 Jun 27;11:50. doi: 10.1186/1472-6882-11-50. PMID: 21708034; PMCID: PMC3141601. Daily JW, Yang M, Park S. Efficacy of Turmeric Extracts and Curcumin for Alleviating the Symptoms of Joint Arthritis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. J Med Food. 2016 Aug;19(8):717-29. doi: 10.1089/jmf.2016.3705. PMID: 27533649; PMCID: PMC5003001. Chin KY. The spice for joint inflammation: anti-inflammatory role of curcumin in treating osteoarthritis. Drug Des Devel Ther. 2016 Sep 20;10:3029-3042. doi: 10.2147/DDDT.S117432. PMID: 27703331; PMCID: PMC5036591. Zhang Y, Zeng Y. Curcumin reduces inflammation in knee osteoarthritis rats through blocking TLR4 /MyD88/NF-κB signal pathway. Drug Dev Res. 2019 May;80(3):353-359. doi: 10.1002/ddr.21509. Epub 2019 Jan 21. PMID: 30663793. Perkins K, Sahy W, Beckett RD. Efficacy of Curcuma for Treatment of Osteoarthritis. J Evid Based Complementary Altern Med. 2017 Jan;22(1):156-165. doi: 10.1177/2156587216636747. Epub 2016 Mar 14. PMID: 26976085; PMCID: PMC5871206. Abdel-Tawab M, Werz O, Schubert-Zsilavecz M. Boswellia serrata: an overall assessment of in vitro, preclinical, pharmacokinetic and clinical data. Clin Pharmacokinet. 2011 Jun;50(6):349-69. doi: 10.2165/11586800-000000000-00000. PMID: 21553931. Siddiqui MZ. Boswellia serrata, a potential antiinflammatory agent: an overview. Indian J Pharm Sci. 2011 May;73(3):255-61. doi: 10.4103/0250-474X.93507. PMID: 22457547; PMCID: PMC3309643. Majeed M, Majeed S, Narayanan NK, Nagabhushanam K. A pilot, randomized, double-blind, placebo-controlled trial to assess the safety and efficacy of a novel Boswellia serrata extract in the management of osteoarthritis of the knee. Phytother Res. 2019 May;33(5):1457-1468. doi: 10.1002/ptr.6338. Epub 2019 Mar 6. PMID: 30838706; PMCID: PMC6681146. Kimmatkar N, Thawani V, Hingorani L, Khiyani R. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial. Phytomedicine. 2003 Jan;10(1):3-7. doi: 10.1078/094471103321648593. PMID: 12622457. Yu G, Xiang W, Zhang T, Zeng L, Yang K, Li J. Effectiveness of Boswellia and Boswellia extract for osteoarthritis patients: a systematic review and meta-analysis. BMC Complement Med Ther. 2020 Jul 17;20(1):225. doi: 10.1186/s12906-020-02985-6. PMID: 32680575; PMCID: PMC7368679. Salwowska NM, Bebenek KA, Żądło DA, Wcisło-Dziadecka DL. Physiochemical properties and application of hyaluronic acid: a systematic review. J Cosmet Dermatol. 2016 Dec;15(4):520-526. doi: 10.1111/jocd.12237. Epub 2016 Jun 21. PMID: 27324942. Faust HJ, Sommerfeld SD, Rathod S, Rittenbach A, Ray Banerjee S, Tsui BMW, Pomper M, Amzel ML, Singh A, Elisseeff JH. A hyaluronic acid binding peptide-polymer system for treating osteoarthritis. Biomaterials. 2018 Nov;183:93-101. doi: 10.1016/j.biomaterials.2018.08.045. Epub 2018 Aug 21. PMID: 30149233. Lin W, Liu Z, Kampf N, Klein J. The Role of Hyaluronic Acid in Cartilage Boundary Lubrication. Cells. 2020 Jul 2;9(7):1606. doi: 10.3390/cells9071606. PMID: 32630823; PMCID: PMC7407873. Pontes-Quero GM, García-Fernández L, Aguilar MR, San Román J, Pérez Cano J, Vázquez-Lasa B. Active viscosupplements for osteoarthritis treatment. Semin Arthritis Rheum. 2019 Oct;49(2):171-183. doi: 10.1016/j.semarthrit.2019.02.008. Epub 2019 Feb 19. PMID: 30878154. Tashiro T, Seino S, Sato T, Matsuoka R, Masuda Y, Fukui N. Oral administration of polymer hyaluronic acid alleviates symptoms of knee osteoarthritis: a double-blind, placebo-controlled study over a 12-month period. ScientificWorldJournal. 2012;2012:167928. doi: 10.1100/2012/167928. Epub 2012 Nov 20. PMID: 23226979; PMCID: PMC3512263. Ricci M, Micheloni GM, Berti M, Perusi F, Sambugaro E, Vecchini E, Magnan B. Clinical comparison of oral administration and viscosupplementation of hyaluronic acid (HA) in early knee osteoarthritis. Musculoskelet Surg. 2017 Apr;101(1):45-49. doi: 10.1007/s12306-016-0428-x. Epub 2016 Sep 28. PMID: 27681813. Directions: take 3 tablets a day with water.
|
| 60 tablets | |
| Nutrition information | |
| Daily dose 3 tablets | |
| Servings per container:20 | |
| Per daily dose (3 tablets) | |
|
Glucosamine
|
500 mg |
|
MSM
|
500 mg |
|
Curcuminoids Curcugreen™
|
237,5 mg |
|
Boswellia BosLIQ®
of which AKBA
other β-boswellic acids
total diterpenes
|
200 mg 10 mg 40 mg 16 mg |
| Hyaluronic acid | 100 mg |
|
Ingredients: bulking agent: cellulose; glucosamine D-sulphate 2KCl (from shellfish), methylsulfonylmethane (MSM), Curcugreen™ [curcuminoids from turmeric rhizome (Curcuma longa L.)], BosLIQ®-AKBA-PWD ( boswellia dry extract (Boswellia sacra Flueck.) gum-resin 5% acetyl-11-keto-β-boswellic acid (AKBA), 20% other β-boswellic acids and 8% total diterpenes), sodium hyaluronate, anti-caking agents: magnesium salts of fatty acids, silicon dioxide.
|
|
Copyright © 2007-2023 IAF NETWORK S.p.A. - All Rights Reserved C.f. e P.Iva 02424060982 - REA: BS-448778 - email: help@iafstore.com 
