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YAMAMOTO RESEARCH
Fosfatidilserina 60 capsules

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$ 17,33 $ 20,39

 


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Yamamoto® Research Fosfatidilserina 60 capsules. Fosfatidilserina is a food supplement providing 20 mg per daily dose of phosphatidylserine, a phospholipid and a natural component of the cell membrane.

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Yamamoto Research - Fosfatidilserina - IAFSTORE.COM

YAMAMOTO® RESEARCH
Yamamoto® Research Fosfatidilserina

Fosfatidilserina is a food supplement providing 20 mg per daily dose of phosphatidylserine, a phospholipid and a natural component of the cell membrane.

The notoriety that Phosphatidylserine is gaining is basically due to its 'restorative' action and 'nutritional' support for the central nervous system, capable of improving cognitive function, the transmission of stimuli between nerve cells and as an essential component of cell membranes (especially nerve membranes) necessary for the entry of nutrients and the relative expulsion of waste materials, as well as having demonstrated an interesting hepatic detoxifying action.

Phosphatidylserine is a phospholipid, specifically a glycerophospholipid, consisting of two fatty acid molecules linked to a glycerol molecule and an ethanolamine phosphate molecule, which is found mainly in the central nervous system and the brain. Phosphatidylserine plays an essential role in the membranes of cells (particularly neurons), the integrity and permeability of which it regulates. Brain tissue has a high concentration of phosphatidylserine, which promotes the development of memory, concentration, learning and true neuroprotection. In addition to this, at the cellular level, it has been further demonstrated that Phosphatidylserine enhances energy metabolism in all cells. The fact is that phosphatidylserine content decreases with age, and because it preserves the integrity of cell membranes, its support promotes efficient and 'slow aging' nerve intercellular connections that maintain greater cognitive efficiency and promote a more relaxed state before and after times of particular stress.

Several double-blind studies suggest that Phosphatidylserine may be useful in maintaining cognitive function and memory in elderly subjects.

SCIENTIFIC REFERENCES

Glade MJ, Smith K. Phosphatidylserine and the human brain. Nutrition. 2015 Jun;31(6):781-6. doi: 10.1016/j.nut.2014.10.014. Epub 2014 Nov 4. PMID: 25933483.

Kim HY, Huang BX, Spector AA. Phosphatidylserine in the brain: metabolism and function. Prog Lipid Res. 2014 Oct;56:1-18. doi: 10.1016/j.plipres.2014.06.002. Epub 2014 Jun 30. PMID: 24992464; PMCID: PMC4258547.

Scott-Hewitt N, Perrucci F, Morini R, Erreni M, Mahoney M, Witkowska A, Carey A, Faggiani E, Schuetz LT, Mason S, Tamborini M, Bizzotto M, Passoni L, Filipello F, Jahn R, Stevens B, Matteoli M. Local externalization of phosphatidylserine mediates developmental synaptic pruning by microglia. EMBO J. 2020 Aug 17;39(16):e105380. doi: 10.15252/embj.2020105380. Epub 2020 Jul 13. PMID: 32657463; PMCID: PMC7429741.

Borghese CM, Gómez RA, Ramírez OA. Phosphatidylserine increases hippocampal synaptic efficacy. Brain Res Bull. 1993;31(6):697-700.

Kidd PM. Phosphatidylserine; membrane nutrient for memory. A clinical and mechanistic assessment. Altern Med Rev 1996;1:70-84.

Zamanian G, Partoazar A, Tavangar SM, Rashidian A, Mirzaei P, Niaz Q, Sharifi K, Dehpour AR, Jazaeri F. Effect of phosphatidylserine on cirrhosis-induced hepatic encephalopathy: Response to acute endotoxemia in cirrhotic rats. Life Sci. 2020 Jul 15;253:117606. doi: 10.1016/j.lfs.2020.117606. Epub 2020 Apr 19. PMID: 32320707.

Hirayama S, Terasawa K, Rabeler R, Hirayama T, Inoue T, Tatsumi Y, Purpura M, Jäger R. The effect of phosphatidylserine administration on memory and symptoms of attention-deficit hyperactivity disorder: a randomised, double-blind, placebo-controlled clinical trial. J Hum Nutr Diet. 2014 Apr;27 Suppl 2:284-91. doi: 10.1111/jhn.12090. Epub 2013 Mar 17. PMID: 23495677.

Moré MI, Freitas U, Rutenberg D. Positive effects of soy lecithin-derived phosphatidylserine plus phosphatidic acid on memory, cognition, daily functioning, and mood in elderly patients with Alzheimer's disease and dementia. Adv Ther. 2014 Dec;31(12):1247-62. doi: 10.1007/s12325-014-0165-1. Epub 2014 Nov 21. PMID: 25414047; PMCID: PMC4271139.

Ye M, Han BH, Kim JS, Kim K, Shim I. Neuroprotective Effect of Bean Phosphatidylserine on TMT-Induced Memory Deficits in a Rat Model. Int J Mol Sci. 2020 Jul 11;21(14):4901. doi: 10.3390/ijms21144901. PMID: 32664537; PMCID: PMC7402346.

Toffano G. The therapeutic value of phosphatidylserine effect in the aging brain. In: Hanin L, Ansell GB, eds. Lecithin: Technological, Biological and Therapeutic Aspects. New York: Plenum Press; 1987:137-46.

Nunzi MG, et al. Therapeutic properties of phosphatidylserine in the aging brain. In: Hanin I, Pepeu G, eds. Phospholipids: Biochemical, Pharmaceutical and Analytical Considerations. New York: Plenum Press; 1990:213-8.

Directions: take 1 capsule a day with water.


Net content: 36 g

Storage: keep tightly closed in a cool and dry place.


Warnings: do not exceed the recommended daily dose. Supplements are not intended as a substitute for a varied diet. A varied and balanced diet and a healthy lifestyle are important. Keep out of the reach of children under three years of age. Keep in a cold and dry place. Avoid exposure to heat sources and sunlight. Do not disperse in the environment after use.


60 capsules
 
Nutrition information
Daily dose: 1 capsule
Servings per container: 60
 
  Per daily dose (1 capsule)
Phosphatidylserine 20 mg
   
Ingredients: bulking agents: cellulose, dicalcium phosphate; vegetable capsule (glazing agent: hydroxypropylmethylcellulose), phosphadylserine, anti-caking agents: magnesium salt of fatty acids, silicon dioxide.

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