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Home › Health and wellness › Digestive and Intestine › Intestine
Lactomel® 30 capsules - YAMAMOTO RESEARCH

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YAMAMOTO RESEARCH
Lactomel® 30 capsules

Rating 4,65/5 (Number of votes: 20)
Customer Reviews: 2

Yamamoto® Research Lactomel® 30 capsules. Lactomel is a food supplement that provides 500 mg of apple extract per daily dose and the tindalized prebiotic microorganism Lactobacillus plantarum . Prebiotics favor the balance of the intestinal flora.

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Yamamoto Research - Lactomel® - IAFSTORE.COM

YAMAMOTO® RESEARCH
Yamamoto® Research Lactomel® - Food supplement based on apple extract and Lactobacillus plantarum

Lactomel is a food supplement that provides 500 mg of apple extract per daily dose and the tindalized prebiotic microorganism Lactobacillus plantarum. Prebiotics favor the balance of the intestinal flora.

LACTOMEL is a supplement containing Lactobacillus plantarum in a tindalised form and apple extract that can benefit the health and well-being of intestinal flora.

Lactobacillus plantarum is one of the most 'hardy' strains of probiotics due to its ability to withstand and adapt to various temperatures between 15-45°C and even pH levels as low as 3.2. It is also able to tolerate both acid and bile salts, which means that it can survive while passing through the gastrointestinal tract. Once it has arrived at its 'destination', it has been shown to help prevent pathogens from settling in the intestine by preventing them from 'sticking' to the intestinal wall (e.g. against Candida albicans and Escherichia Coli) while also promoting a valuable immune response and direct 'antimicrobial' action in situ.

Another important benefit of L. plantarum is its ability to help repair the intestinal lining and reduce inflammation, where it is particularly indicated in the treatment of irritable bowel syndrome and colitis. The most recent clinical research also reveals its favourable action on serotonin and dopamine, opening up scenarios for potential improvement in states of anxiety and depression.

LACTOMEL contains apple extract, a valuable 'élisir' of elements such as various polyphenols, including pectin, a type of soluble fibre that acts as its own prebiotic, nourishing and promoting the growth of positive bacteria in the intestine, maintaining intestinal regularity (see constipation or dysentery) and improving the condition of the intestinal barrier.

SCIENTIFIC LITERATURE

Seddik HA, Bendali F, Gancel F, Fliss I, Spano G, Drider D. Lactobacillus plantarum and Its Probiotic and Food Potentialities. Probiotics Antimicrob Proteins. 2017 Jun;9(2):111-122. doi: 10.1007/s12602-017-9264-z. PMID: 28271469.

Flórez AB, Egervärn M, Danielsen M, Tosi L, Morelli L, Lindgren S, Mayo B. Susceptibility of Lactobacillus plantarum strains to six antibiotics and definition of new susceptibility-resistance cutoff values. Microb Drug Resist. 2006 Winter;12(4):252-6. doi: 10.1089/mdr.2006.12.252. PMID: 17227210.

Le B, Yang SH. Efficacy of Lactobacillus plantarum in prevention of inflammatory bowel disease. Toxicol Rep. 2018 Mar 2;5:314-317. doi: 10.1016/j.toxrep.2018.02.007. PMID: 29854599; PMCID: PMC5977373.

Mileti E, Matteoli G, Iliev ID, Rescigno M. Comparison of the immunomodulatory properties of three probiotic strains of Lactobacilli using complex culture systems: prediction for in vivo efficacy. PLoS One. 2009 Sep 16;4(9):e7056. doi: 10.1371/journal.pone.0007056. PMID:

Murofushi Y, Villena J, Morie K, Kanmani P, Tohno M, Shimazu T, Aso H, Suda Y, Hashiguchi K, Saito T, Kitazawa H. The toll-like receptor family protein RP105/MD1 complex is involved in the immunoregulatory effect of exopolysaccharides from Lactobacillus plantarum N14. Mol Immunol. 2015 Mar;64(1):63-75. doi: 10.1016/j.molimm.2014.10.027. Epub 2014 Nov 13. PMID: 25466614.

Palacios S, Espadaler J, Fernández-Moya JM, Prieto C, Salas N. Is it possible to prevent recurrent vulvovaginitis? The role of Lactobacillus plantarum I1001 (CECT7504). Eur J Clin Microbiol Infect Dis. 2016 Oct;35(10):1701-8. doi: 10.1007/s10096-016-2715-8. Epub 2016 Jul 9. PMID: 27393491; PMCID: PMC5035666.

Ducrotté P, Sawant P, Jayanthi V. Clinical trial: Lactobacillus plantarum 299v (DSM 9843) improves symptoms of irritable bowel syndrome. World J Gastroenterol. 2012;18(30):4012-4018. doi:10.3748/wjg.v18.i30.4012

Liu YW, Liong MT, Tsai YC. New perspectives of Lactobacillus plantarum as a probiotic: The gut-heart-brain axis. J Microbiol. 2018 Sep;56(9):601-613. doi: 10.1007/s12275-018-8079-2. Epub 2018 Aug 23. PMID: 30141154.

Fei Zhang, Yue Li, Xiliang Wang, Shengping Wang, Dingren Bi, "The Impact ofLactobacillus plantarum on the Gut Microbiota of Mice with DSS-Induced Colitis",BioMed Research International, vol. 2019, Article ID 3921315, 10 pages, 2019.https://doi.org/10.1155/2019/3921315

Liu YW, Liu WH, Wu CC, Juan YC, Wu YC, Tsai HP, Wang S, Tsai YC. Psychotropic effects of Lactobacillus plantarum PS128 in early life-stressed and naïve adult mice. Brain Res. 2016 Jan 15;1631:1-12. doi: 10.1016/j.brainres.2015.11.018. Epub 2015 Nov 24. PMID: 26620542.

Liu F, Wang X, Li D, Cui Y, Li X. Apple polyphenols extract alleviated dextran sulfate sodium-induced ulcerative colitis in C57BL/6 male mice by restoring bile acid metabolism disorder and gut microbiota dysbiosis. Phytother Res. 2021 Mar;35(3):1468-1485. doi: 10.1002/ptr.6910. Epub 2020 Nov 20. PMID: 33215776.

Li D, Cui Y, Wang X, Liu F, Li X. Apple Polyphenol Extract Improves High-Fat Diet-Induced Hepatic Steatosis by Regulating Bile Acid Synthesis and Gut Microbiota in C57BL/6 Male Mice. J Agric Food Chem. 2021 Jun 23;69(24):6829-6841. doi: 10.1021/acs.jafc.1c02532. Epub 2021 Jun 14. PMID: 34124904.

Elshahed MS, Miron A, Aprotosoaie AC, Farag MA. Pectin in diet: Interactions with the human microbiome, role in gut homeostasis, and nutrient-drug interactions. Carbohydr Polym. 2021 Mar 1;255:117388. doi: 10.1016/j.carbpol.2020.117388. Epub 2020 Nov 9. PMID: 33436217.

Beukema M, Faas MM, de Vos P. The effects of different dietary fiber pectin structures on the gastrointestinal immune barrier: impact via gut microbiota and direct effects on immune cells. Exp Mol Med. 2020 Sep;52(9):1364-1376. doi: 10.1038/s12276-020-0449-2. Epub 2020 Sep 10. PMID: 32908213; PMCID: PMC8080816.

DIRECTIONS: take 1 capsule a day with water.


Net content: 24 g


Warnings: do not exceed the recommended daily dose. Supplements are not intended as a substitute for a varied diet. A varied and balanced diet and a healthy lifestyle are important. Keep out of the reach of children under three years of age. Keep in a cold and dry place. Avoid exposure to heat sources and sunlight.

30 capsules  
Nutrition information 
  Per daily dose (1 capsule)
   
Dry apple extract
 500 mg
Lactobacillus plantarum
 3x10⁹ UFC*
   
* UFC: colony forming units
Ingredients: dry apple extract (Malus pumilaMill.), Fruit; vegetable capsule (coating agent: hydroxy-propyl-methylcellulose), bulking agents: cellulose, dicalcium phosphate; Lactobacillus plantarum (Lactiplantibacillus plantarumsubsp. Plantarum) 14D tindalized (CECT 4528), anti-caking agents: silicon dioxide, magnesium salts of fatty acids.

CASE: PAP 21>
BLISTER PAPER COLLECTION : C / PVC 90> PLASTIC COLLECTION
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Customer Reviews (2)

Reviews from customers who have purchased the product are marked "Verified Purchase"
molto ssoddisfatto del prodotto…
by USER ID 599457 on 20/08/2019
molto ssoddisfatto del prodotto e del servizio iaf, consigliato
Produit fantastique ... IAFSTORE…
by USER ID 590453 on 04/07/2019
Produit fantastique ... IAFSTORE le meilleur!
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