YAMAMOTO RESEARCH
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The pomegranate (or rather pomegranate) is the fruit of the Punica granatum, a plant cultivated in Mediterranean areas, India, Iran and the Caucasus. The kernels of this fruit are characterised by a very sweet flavour and distinctive shape. They are not only good: they also provide numerous benefits. Pomegranates contain large quantities of antioxidants, vitamin C and provitamin A, as well as polyphenols, which are useful in combating oxidative stress.
In ancient times, this fruit was used to soothe heartburn, but also as a mild aphrodisiac. The substances it contains can provide numerous benefits, and are recognised as having antioxidant, anticoagulant, vasoprotective and astringent properties. Because of these properties, concentrated pomegranate juice is used in the manufacture of various supplements, mainly for antioxidant and refreshing purposes. What is Melagrana Melagrana is a dietary supplement containing pomegranate juice, which is important for its antioxidant activity. In addition, **zinc contributes to the normal metabolism of macronutrients, particularly carbohydrates and fatty acids. Pomegranate is a drink with a very distinctive, pleasant and refreshing flavour derived from the mechanical pressing of the kernels characterising this beautiful fruit, which is often regarded as a true 'èlisir' of youth for our health. The beneficial effects derived from consuming pomegranate are linked to the presence in its composition of a high concentration of substances with high antioxidant power such as flavonoids, anthocyanins, polyphenols and tannins. Powerful representatives of all these molecules are ellagic acid (a natural phenolic antioxidant with proven efficacy) and punicic acid (a polyunsaturated fatty acid with high therapeutic potential), as well as vitamins C, A, E, iron and potassium. Benefits of our supplement Why choose Melagrana: - Powerful natural antioxidant; - Supplemented with Zinc; - Pleasant refreshing drink to enjoy anytime; - Counteracts oxidative stress; - Cardiovascular function. When and how to take it We recommend taking 25 ml of the drink per day, either pure or diluted with water. It can be taken with meals, e.g. as an accompaniment to breakfast, or on an empty stomach. SCIENTIFIC REFERENCES
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Jurenka JS. Therapeutic applications of pomegranate (Punica granatum L.): a review. Altern Med Rev. 2008 Jun;13(2):128-44. PMID: 18590349. Fahmy H , Hegazi N , El-Shamy S , Farag MA . Pomegranate juice as a functional food: a comprehensive review of its polyphenols, therapeutic merits, and recent patents. Food Funct. 2020 Jul 1;11(7):5768-5781. doi: 10.1039/d0fo01251c. Epub 2020 Jul 1. PMID: 32608443. Sahebkar A, Ferri C, Giorgini P, Bo S, Nachtigal P, Grassi D. Effects of pomegranate juice on blood pressure: A systematic review and meta-analysis of randomized controlled trials. Pharmacol Res. 2017 Jan;115:149-161. doi: 10.1016/j.phrs.2016.11.018. Epub 2016 Nov 23. PMID: 27888156. Ammar A, Turki M, Hammouda O, Chtourou H, Trabelsi K, Bouaziz M, Abdelkarim O, Hoekelmann A, Ayadi F, Souissi N, Bailey SJ, Driss T, Yaich S. Effects of Pomegranate Juice Supplementation on Oxidative Stress Biomarkers Following Weightlifting Exercise. Nutrients. 2017 Jul 29;9(8):819. doi: 10.3390/nu9080819. PMID: 28758938; PMCID: PMC5579613. Barati Boldaji R, Akhlaghi M, Sagheb MM, Esmaeilinezhad Z. Pomegranate juice improves cardiometabolic risk factors, biomarkers of oxidative stress and inflammation in hemodialysis patients: a randomized crossover trial. J Sci Food Agric. 2020 Jan 30;100(2):846-854. doi: 10.1002/jsfa.10096. Epub 2019 Nov 21. PMID: 31646650. Danesi F, Ferguson LR. Could Pomegranate Juice Help in the Control of Inflammatory Diseases? Nutrients. 2017 Aug 30;9(9):958. doi: 10.3390/nu9090958. PMID: 28867799; PMCID: PMC5622718. Wang D, Özen C, Abu-Reidah IM, Chigurupati S, Patra JK, Horbanczuk JO, Jóźwik A, Tzvetkov NT, Uhrin P, Atanasov AG. Vasculoprotective Effects of Pomegranate (Punica granatum L.). Front Pharmacol. 2018 May 24;9:544. doi: 10.3389/fphar.2018.00544. PMID: 29881352; PMCID: PMC5977444. Aviram M, Rosenblat M, Gaitini D, Nitecki S, Hoffman A, Dornfeld L, Volkova N, Presser D, Attias J, Liker H, Hayek T. Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation. Clin Nutr. 2004 Jun;23(3):423-33. doi: 10.1016/j.clnu.2003.10.002. Erratum in: Clin Nutr. 2008 Aug;27(4):671. PMID: 15158307. El-Sayyad HIH, El-Gallil HA, El-Ghaweet HA. Synergistic effects of pomegranate juice and atorvastatin for improving cerebellar structure and function of breast-feeding rats maternally fed on a high cholesterol diet. J Chem Neuroanat. 2020 Sep;107:101798. doi: 10.1016/j.jchemneu.2020.101798. Epub 2020 Apr 25. PMID: 32339653. Aviram M, Rosenblat M. Pomegranate for your cardiovascular health. Rambam Maimonides Med J. 2013 Apr 30;4(2):e0013. doi: 10.5041/RMMJ.10113. PMID: 23908863; PMCID: PMC3678830. Delgado NTB, Rouver WN, Dos Santos RL. Protective Effects of Pomegranate in Endothelial Dysfunction. Curr Pharm Des. 2020;26(30):3684-3699. doi: 10.2174/1381612826666200406152147. PMID: 32250215. Vlachojannis C, Erne P, Schoenenberger AW, Chrubasik-Hausmann S. A critical evaluation of the clinical evidence for pomegranate preparations in the prevention and treatment of cardiovascular diseases. Phytother Res. 2015 Apr;29(4):501-8. doi: 10.1002/ptr.5280. Epub 2015 Jan 22. PMID: 25611333. Sharma P, McClees SF, Afaq F. Pomegranate for Prevention and Treatment of Cancer: An Update. Molecules. 2017 Jan 24;22(1):177. doi: 10.3390/molecules22010177. PMID: 28125044; PMCID: PMC5560105. Hou C, Zhang W, Li J, Du L, Lv O, Zhao S, Li J. Beneficial Effects of Pomegranate on Lipid Metabolism in Metabolic Disorders. Mol Nutr Food Res. 2019 Aug;63(16):e1800773. doi: 10.1002/mnfr.201800773. Epub 2019 Feb 7. PMID: 30677224. Saeed M, Naveed M, BiBi J, Kamboh AA, Arain MA, Shah QA, Alagawany M, El-Hack MEA, Abdel-Latif MA, Yatoo MI, Tiwari R, Chakraborty S, Dhama K. The Promising Pharmacological Effects and Therapeutic/Medicinal Applications of Punica Granatum L. (Pomegranate) as a Functional Food in Humans and Animals. Recent Pat Inflamm Allergy Drug Discov. 2018;12(1):24-38. doi: 10.2174/1872213X12666180221154713. PMID: 29473532.
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Nutrition information | ||
Per daily dose (25 ml) |
%RI* | |
Pomegranate juice
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4 g | - |
Zinc
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10 mg | 100 |
*RI = Reference Intake
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Ingredients: purified water, concentrated pomegranate juice (Punica granatum L.) fruit, zinc gluconate, preservatives: potassium sorbate, sodium benzoate; natural flavour, sweetener: sucralose.
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