E-mail  
       
Password  
     
   
 


  Haven't you got an account yet? Subscribe for free


Insert the e-mail address used for log-in

E-mail  
       
 
POST A REVIEW

The submission of reviews is free, but users agree not to post comments unlawful, defamatory, libelous, vulgar, profane, libelous, invasive of another's privacy. We will not publish comments that contain promotions for parties or movements praising fanaticism, racism, class hatred, they are not also published comments that provide confidential information learned under an employment relationship, those that contain personal data or numbers telephone, those offensive patents, trademarks, copyrights or other intellectual and industrial property rights of third parties, those in advertising and commercial content, and finally those that use coded messages. The contents of each comment represent the views of the author. Iafstore reserves the right to remove, without notice and at its sole discretion, comments that do not comply with such regulations. Iafstore reserves also collected and stored the identification data, date, time of the computer that published the comments in order to deliver them upon request to the competent authorities.
 
Your shopping cart is empty

YAMAMOTO RESEARCH
Sament® 60 capsules

Rating 5/5 (Number of votes: 1) vote

Price:

$ 25,91 $ 28,79

 


In stock

 


 


Yamamoto® Research Sament® 60 capsules. Sament® is a food supplement with phosphatidylserine, acetylcarnitine and extracts of hericium and rhodiola.

See description


 
Yamamoto Research - Mindfullness - IAFSTORE.COM

YAMAMOTO® RESEARCH
Yamamoto® Research Sament®

Sament is a food supplement with phosphatidylserine, acetylcarnitine and extracts of hericium and rhodiola.

We are in the era in which maximum performance is required, rapid times and everything is done as if it were a great competition for maximum production "yield". But many times it happens that it becomes more and more difficult to maintain the rhythm of our daily life, the brilliance and the right focus for our activities, and in the long run, the pressing and continuous stimulation on our "sympathetic" nervous system can send it into "tilt" . This means deificit in concentration, memory, chronic fatigue and anxiety related "stress" disorders. In this regard, nutraceuticals comes to support us with various elements of real effectiveness, to ensure that our neuroendocrine system can better respond and withstand these phases of high stress,

Sament® is a tonic-adaptogen supplement that allows you to better face and overcome phases of particular stress and psychophysical fatigue based on: acetylcarnitine, phosphatidylserine, Hericium and Rodiola rosea.

Acetylcarnitine is the acetylated form of L-Carnitine that is able to cross the blood brain barrier and reach the cell membranes of different tissues, including the brain. It is considered a nootropic and a neuroprotector on neurotransmitters, which promotes synaptic plasticity, a precursor of acetylcholine which favors the reactivity of reflexes, but above all the capacity of memory and learning, and in addition to favoring concentration and brain energy. , thanks to its transport of fatty acids to the mitochondria.

Phosphatidylserine (PS) is probably one of the most effective and important natural nootropics we have available today. Phosphatidylseria is able to keep our brain cells healthy, improving the alertness, attention, focus, memory, and mood tone. Phosphatidylserine is a phospholipid of fundamental importance for the walls of the cell membranes of the brain, as well as being found in all cells, and helps to maintain the efficiency of the permeability of brain cells. Phosphatidylserine is involved in the formation and sending of signals within neurons which occurs through neural synapses.
memory and data storage. Phosphatidylserine is also involved in the construction of mitochondria which are the energy centers of each cell.

Hericium Erinaceus is one of the most respected and used medicinal mushrooms in oriental and traditional medicines, thanks to the presence of its bioactive elements extracted from its fruiting body or mycelium which possess numerous beneficial properties for the whole organism. These active substances are able to cross the blood brain barrier and are able to induce the gene expression of the neuronal growth factor (NGF - Nerve Growth Factor) a protein that plays an important role in the maintenance, survival and regeneration of neurons, and it is required by the brain itself to keep neurons strong and healthy. Hericium is increasingly considered today as a true "antiaging" of our neurons that remain stronger and healthier, stimulating their repair and the creation of new ones,

Rodiola Rosea is considered an "adaptogen" par excellence that helps to better deal with stress and fatigue, increasing energy yield, alertness and physical endurance, increasing mental performance during periods of chronic stress. It too can be considered an excellent natural nootropic capable of improving concentration and mood by influencing the levels of serotonin and norepinephrine in the brain and "feel-good" opioids such as beta-endorphins. It is capable of promoting neuronal regeneration and helps in neurogenesis itself by growing new neurons. Its action also becomes pro-energetic by promoting the synthesis of ATP, the main source of energy of the organism and of the brain cells themselves.

SCIENTIFIC REFERENCES

Rebouche CJ. Kinetics, pharmacokinetics, and regulation of L-carnitine and acetyl-L-carnitine metabolism. Ann N Y Acad Sci. 2004 Nov;1033:30-41. doi: 10.1196/annals.1320.003. PMID: 15591001.

Rosca MG, Lemieux H, Hoppel CL. Mitochondria in the elderly: Is acetylcarnitine a rejuvenator? Adv Drug Deliv Rev. 2009 Nov 30;61(14):1332-1342. doi: 10.1016/j.addr.2009.06.009. Epub 2009 Aug 29. PMID: 19720100; PMCID: PMC4120470.

Liu J, Head E, Kuratsune H, Cotman CW, Ames BN. Comparison of the effects of L-carnitine and acetyl-L-carnitine on carnitine levels, ambulatory activity, and oxidative stress biomarkers in the brain of old rats. Ann N Y Acad Sci. 2004 Nov;1033:117-31. doi: 10.1196/annals.1320.011. PMID: 15591009.

White HL, Scates PW. Acetyl-L-carnitine as a precursor of acetylcholine. Neurochem Res. 1990 Jun;15(6):597-601. doi: 10.1007/BF00973749. PMID: 2215852.

Ferreira GC, McKenna MC. L-Carnitine and Acetyl-L-carnitine Roles and Neuroprotection in Developing Brain. Neurochem Res. 2017 Jun;42(6):1661-1675. doi: 10.1007/s11064-017-2288-7. Epub 2017 May 16. PMID: 28508995; PMCID: PMC5621476.

Glade MJ, Smith K. Phosphatidylserine and the human brain. Nutrition. 2015 Jun;31(6):781-6. doi: 10.1016/j.nut.2014.10.014. Epub 2014 Nov 4. PMID: 25933483.

Kim HY, Huang BX, Spector AA. Phosphatidylserine in the brain: metabolism and function. Prog Lipid Res. 2014 Oct;56:1-18. doi: 10.1016/j.plipres.2014.06.002. Epub 2014 Jun 30. PMID: 24992464; PMCID: PMC4258547.

Leventis PA, Grinstein S. The distribution and function of phosphatidylserine in cellular membranes. Annu Rev Biophys. 2010;39:407-27. doi: 10.1146/annurev.biophys.093008.131234. PMID: 20192774.

Moré MI, Freitas U, Rutenberg D. Positive effects of soy lecithin-derived phosphatidylserine plus phosphatidic acid on memory, cognition, daily functioning, and mood in elderly patients with Alzheimer's disease and dementia. Adv Ther. 2014 Dec;31(12):1247-62. doi: 10.1007/s12325-014-0165-1. Epub 2014 Nov 21. PMID: 25414047; PMCID: PMC4271139.

Friedman M. Chemistry, Nutrition, and Health-Promoting Properties of Hericium erinaceus (Lion's Mane) Mushroom Fruiting Bodies and Mycelia and Their Bioactive Compounds. J Agric Food Chem. 2015 Aug 19;63(32):7108-23. doi: 10.1021/acs.jafc.5b02914. Epub 2015 Aug 5. PMID: 26244378.

Mori K, Obara Y, Moriya T, Inatomi S, Nakahata N. Effects of Hericium erinaceus on amyloid β(25-35) peptide-induced learning and memory deficits in mice. Biomed Res. 2011 Feb;32(1):67-72. doi: 10.2220/biomedres.32.67. PMID: 21383512.

Roda E, Priori EC, Ratto D, De Luca F, Di Iorio C, Angelone P, Locatelli CA, Desiderio A, Goppa L, Savino E, Bottone MG, Rossi P. Neuroprotective Metabolites of Hericium erinaceus Promote Neuro-Healthy Aging. Int J Mol Sci. 2021 Jun 15;22(12):6379. doi: 10.3390/ijms22126379. PMID: 34203691; PMCID: PMC8232141.

Chong PS, Fung ML, Wong KH, Lim LW. Therapeutic Potential of Hericium erinaceusfor Depressive Disorder. Int J Mol Sci. 2019 Dec 25;21(1):163. doi: 10.3390/ijms21010163. PMID: 31881712; PMCID: PMC6982118.

Saitsu Y, Nishide A, Kikushima K, Shimizu K, Ohnuki K. Improvement of cognitive functions by oral intake of Hericium erinaceus. Biomed Res. 2019;40(4):125-131. doi: 10.2220/biomedres.40.125. PMID: 31413233.

Panossian A, Wikman G, Sarris J. Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy. Phytomedicine. 2010 Jun;17(7):481-93. doi: 10.1016/j.phymed.2010.02.002. Epub 2010 Apr 7. PMID: 20378318.

Anghelescu IG, Edwards D, Seifritz E, Kasper S. Stress management and the role of Rhodiola rosea: a review. Int J Psychiatry Clin Pract. 2018 Nov;22(4):242-252. doi: 10.1080/13651501.2017.1417442. Epub 2018 Jan 11. PMID: 29325481.

Amsterdam JD, Panossian AG. Rhodiola rosea L. as a putative botanical antidepressant. Phytomedicine. 2016 Jun 15;23(7):770-83. doi: 10.1016/j.phymed.2016.02.009. Epub 2016 Feb 24. PMID: 27013349.

Cropley M, Banks AP, Boyle J. The Effects of Rhodiola rosea L. Extract on Anxiety, Stress, Cognition and Other Mood Symptoms. Phytother Res. 2015 Dec;29(12):1934-9. doi: 10.1002/ptr.5486. Epub 2015 Oct 27. PMID: 26502953.

Olsson EM, von Schéele B, Panossian AG. A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue. Planta Med. 2009 Feb;75(2):105-12. doi: 10.1055/s-0028-1088346. Epub 2008 Nov 18. PMID: 19016404.

Lekomtseva Y, Zhukova I, Wacker A. Rhodiola rosea in Subjects with Prolonged or Chronic Fatigue Symptoms: Results of an Open-Label Clinical Trial. Complement Med Res. 2017;24(1):46-52. doi: 10.1159/000457918. Epub 2017 Feb 17. PMID: 28219059..

Directions: take 2 capsules a day with water.


Net content: 45 g

Storage: keep tightly closed in a cool and dry place.


Warnings: do not exceed the recommended daily dose. Supplements are not intended as a substitute for a varied diet. A varied and balanced diet and a healthy lifestyle are important. Keep out of the reach of children under three years of age. Keep in a cold and dry place. Avoid exposure to heat sources and sunlight. Do not disperse in the environment after use.


60 capsule
 
Nutrition information
Daily dose: 2 capsules
Servings per container: 30
 
  Per daily dose (2 capsules)
Phosphatidylserine 20 mg
Acetyl L-carnitine 250 mg
Hericium 250 mg
of which polysaccharides 75 mg
Rhodiola 100 mg
of which rosavine 3 mg
of which salidroside 1 mg
of which polyphenols 15 mg
   
Ingredients: bulking agents: cellulose, dicalcium phosphate; vegetable capsule (glazing agent: hydroxypropylmethylcellulose), acetyl L-carnitine hydrochloride, dry extract of hericium (Hericium erinaceus (Bull.) Pers.) sporophore 30% polysaccharides, phosphatidylserine, rhodiola dry extract (Rhodiola rosea L. ) root 3% rosavine 1% salidroside and 15% polyphenols, anti-caking agents: silicon dioxide, magnesium salt of fatty acids.

Customer Reviews (0)

Every week discounts on your favorite products.
Receive our offers by email, we give you 10% discount now!
You can unsubscribe at any time
Privacy Policy