YAMAMOTO RESEARCH
Berberina 30 capsules

Berberina is the Yamamoto Research product based on Berberis extract, titrated at 85% berberine.
Berberine is a natural alkaloid that has been shown to have several beneficial health properties, and is present in several plants, such as Berberis aristata, Berberis vulgaris, Coptis chinensis, and Hydrastis canadensis. Among the positive effects on the body, its ability to reduce blood sugar levels, improve heart and liver health and act as a powerful anti-inflammatory should be noted.

Berberine has been used in traditional medicine in Asia for centuries, but has only recently become a subject of interest to Western researchers. Being a bioactive molecule with high potential, it has been the subject of numerous studies, which have demonstrated its effectiveness in various areas of health.
One of the main effects of Berberine is its ability to lower blood sugar levels: this is particularly useful for people suffering from type 2 diabetes, as because Berberine extract can increase insulin sensitivity and improve blood glucose regulation. Additionally, it may help reduce the risk of complications associated with diabetes, such as neuropathy, retinopathy, and nephropathy.

Berberine has also been shown to have a protective effect on the heart and cardiovascular system. It can reduce LDL (“bad”) cholesterol and triglyceride levels, improve endothelial function, and reduce inflammation. These effects may help reduce the risk of developing heart disease, stroke, and other cardiovascular conditions.
Another important action of this natural alkaloid is its protective action on the liver: recent studies have shown that it can help reduce liver damage caused by toxic substances such as alcohol and chemotherapy, and can also help prevent non-alcoholic fatty liver disease (NAFLD), a disease that can lead to the development of permanent liver damage.
Finally, Berberine is a powerful natural anti-inflammatory, capable of reducing inflammation and pain associated with conditions such as arthritis.

What are the actual health benefits of Berberine?
In summary, Berberine is a powerful natural compound, with multiple health properties: the main benefits derived from taking Berberine involve helping to reduce blood sugar levels, supporting the maintenance of heart and liver health, and in its strong anti-inflammatory action.

Scientific references

Asbaghi O, Ghanbari N, Shekari M, et al. The effect of berberine supplementation on obesity parameters, inflammation and liver function enzymes: a systematic review and meta-analysis of randomized controlled trials. Clin Nutr ESPEN 2020;38:43-9.

Chen YX, Gao QY, Zou TH, et al. Berberine versus placebo for the prevention of recurrence of colorectal adenoma: a multicentre, double-blinded, randomised controlled study. Lancet Gastroenterol Hepatol. 2020;5:267-75.

Beba M, Djafarian K, Shab-Bidar S. Effect of Berberine on C-reactive protein: a systematic review and meta-analysis of randomized controlled trials. Complement Ther Med. 2019;46:81-6.

Lyu Y, Zhang Y, Yang M, et al. Pharmacokinetic interactions between metformin and berberine in rats: Role of oral administration sequences and microbiota. Life Sci. 2019;235:116818.

Xu L, Zhang Y, Xue X, et al. A phase I trial of berberine in Chinese with ulcerative colitis. Cancer Prev Res (Phila). 2020;13:117-26.

Zhang LS, Zhang JH, Feng R, et al. Efficacy and safety of berberine alone or combined with statins for the treatment of hyperlipidemia: a systematic review and meta-analysis of randomized controlled clinical trials. Am J Chin Med 2019;47:751-67.

Qing Y, Dong X, Hongli L, Yanhui L. Berberine promoted myocardial protection of postoperative patients through regulating myocardial autophagy. Biomed Pharmacother. 2018;105:1050-1053.

Ju J, Li J, Lin Q, Xu H. Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials. Phytomedicine. 2018;50:25-34.

Li G, Zhao M, Qiu F, Sun Y, Zhao L. Pharmacokinetic interactions and tolerability of berberine chloride with simvastatin and fenofibrate: an open-label, randomized, parallel study in healthy Chinese subjects. Drug Des Devel Ther. 2018;13:129-139.

Yan HM, Xia MF, Wang Y, Chang XX, Yao XZ, Rao SX, et al. Efficacy of berberine in patients with non-alcoholic fatty liver disease. PLoS One. 2015 Aug 7;10:e0134172. doi: 10.1371/journal.pone.0134172.

Net content: 24 g

STORAGE: keep tightly closed in a cool, dry place. Avoid exposure to heat sources and sunlight.

Warnings: do not exceed the recommended daily dose. Supplements are not intended as substitutes for a varied diet. A varied and balanced diet and a healthy lifestyle are important. Keep out of reach of children under three years of age. Do not use during pregnancy or in children, or in any case for prolonged periods, without consulting your doctor.