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YAMAMOTO RESEARCH
Acido lipoico Retard 20 sachets x 2,5 g

Rating 5/5 (Number of votes: 1) vote

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$ 26,99 $ 29,99

 


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Yamamoto® Research Acido lipoico Retard 20 sachets x 2,5 g. Acido lipoico Retard is a food supplement providing 600 mg lipoic acid per daily dose. Product with high M.A.T.R.I.S® microencapsulation technology. It effectively guarantees the absorption of the active ingredients concerned with a gradual release over 8 hours.

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Yamamoto Research - Acido Lipoico Retard - IAFSTORE.COM

YAMAMOTO® RESEARCH
Yamamoto® Research Lipoic acid Retard

LIPOIC ACID RETARD® is a food supplement based on lipoic acid which, thanks to the microencapsulation technology in a matrix "MATRIS®" (Multiform Administration Timed Release Ingredients System), allows to optimize the bioavailability within 8 hours by reducing the number of intakes and masking the unpleasant taste.

Alpha-lipoic acid ("ALA") is a fatty acid characterized by a powerful antioxidant action that helps to counteract the oxidative stress caused by free radicals that accelerate the aging processes and favor the onset of cell damage both to the outside and inside the nerve cell.

Its "protective" role preserves the integrity of the nerve Fibre, thanks to the protective and nourishing activity, making them able to transmit nerve impulses more efficiently. Among the peculiarities of lipoic acid, there is that of being able to reach all cellular compartments and protect them from attack by free radicals, both inside and outside the cell, as well as on the membrane integrity of nerve cells, fundamental for the transmission of nerve impulses, being able to act both in an aqueous (hydrophilic) environment such as the cytoplasm of cells and in a lipophilic environment (such as the cell membrane). promoting the well-being of nerve Fibre and carrying out a general anti-aging action. Lipoic acid protects the integrity of cell membranes and keeps them longer "

Another property related to its powerful antioxidant or "scavenger" action highlighted more recently by alpha-lipoic acid seems to be its ability to counteract cerebral-cognitive aging and the related physiological memory loss that occurs with age. advanced. An antioxidant with very interesting implications in the field of metabolic health but also in the neurocognitive world. Its positive action on the cell membrane has long been known where several studies have documented and confirmed its further role in improving insulin sensitivity (see also in women with polycystic ovary syndrome) where a better absorption of glucose is favored,

Furthermore, alpha-lipoic acid has the characteristics of being able to recycle and regenerate natural water-soluble antioxidants (such as vitamin C and glutathione) and also fat-soluble ones (such as vitamin E and coenzyme Q), amplifying their effects, implementing elements in favor of the contrast to free radicals to protect nerves and blood vessels from continuous attacks by free radicals (ROS), such as during or after sports performance.

Acido lipoco Retard takes advantage of the Matris Retard® patent, capable of increasing absorption and bioavailability, but above all favoring an important controlled release over time.

SCIENTIFIC REFERENCES

Packer L, Witt EH, Tritschler HJ. alpha-Lipoic acid as a biological antioxidant. Free Radic Biol Med. 1995 Aug;19(2):227-50. doi: 10.1016/0891-5849(95)00017-r. PMID: 7649494.

Papanas N, Ziegler D. Efficacy of α-lipoic acid in diabetic neuropathy. Expert Opin Pharmacother. 2014 Dec;15(18):2721-31. doi: 10.1517/14656566.2014.972935. Epub 2014 Nov 10. PMID: 25381809.

Rochette L, Ghibu S, Muresan A, Vergely C. Alpha-lipoic acid: molecular mechanisms and therapeutic potential in diabetes. Can J Physiol Pharmacol. 2015 Dec;93(12):1021-7. doi: 10.1139/cjpp-2014-0353. Epub 2015 Sep 25. PMID: 26406389.

Shay KP, Moreau RF, Smith EJ, Smith RI, Hagen TM. Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential. Biochim Biophys Acta. 2009 Oct;1790(10):1149-60. doi: 10.1016/j.bbagen.2009.07.026. Epub 2009 Aug 4. PMID: 19664690; PMCID: PMC2756298.

Bartkoski S, Day M. Alpha-Lipoic Acid for Treatment of Diabetic Peripheral Neuropathy. Am Fam Physician. 2016 May 1;93(9):786. PMID: 27175957.

Rahimlou M, Asadi M, Banaei Jahromi N, Mansoori A. Alpha-lipoic acid (ALA) supplementation effect on glycemic and inflammatory biomarkers: A Systematic Review and meta- analysis. Clin Nutr ESPEN. 2019 Aug;32:16-28. doi: 10.1016/j.clnesp.2019.03.015. Epub 2019 May 2. PMID: 31221283.

ibullo D, Li Volti G, Giallongo C, Grasso S, Tomassoni D, Anfuso CD, Lupo G, Amenta F, Avola R, Bramanti V. Biochemical and clinical relevance of alpha lipoic acid: antioxidant and anti-inflammatory activity, molecular pathways and therapeutic potential. Inflamm Res. 2017 Nov;66(11):947-959. doi: 10.1007/s00011-017-1079-6. Epub 2017 Jul 4. PMID: 28676917.

Bilska A, Włodek L. Lipoic acid - the drug of the future? Pharmacol Rep. 2005 Sep-Oct;57(5):570-7. PMID: 16227639.

DIRECTIONS: dissolve the contents of 1 sachet in 200 ml of water and take once a day.

Net content: 50 g


Warnings: do not exceed the recommended daily dose. Supplements are not intended as a substitute for a varied diet. A varied and balanced diet and a healthy lifestyle are important. Keep out of the reach of children under three years of age. Per the use of the product it is advisable to consult the doctor. In rare cases, lipoic acid can cause hypoglycemia. Keep in a cold and dry place. Avoid exposure to heat sources and sunlight.


Nutrition information Per daily dose (1 sachet = 2.5 g)
   
Lipoic acid (MATRIS® Thioctic Acid) 600 mg
   
Ingredients: acidity regulator: citric acid; MATRIS® Retard lipoic acid (lipoic acid, anti-caking agent: talc; emulsifier: ethylcellulose; coating agent: silicon dioxide), thickener: carrageenan; flavoring, sweetener: sucralose; anti-caking agent: silicon dioxide; dyes: beta-carotene, beetroot red.

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